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The role of DOCK10 in the regulation of the transcriptome and aging

DOCK10, a guanine-nucleotide exchange factor (GEF) for Rac1 and Cdc42 Rho GTPases whose expression is induced by interleukin-4 (IL-4) in B cells, is involved in B cell development and function according to recent studies performed in Dock10-knockout (KO) mice. To investigate whether DOCK10 is involv...

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Detalles Bibliográficos
Autores principales:	Ruiz-Lafuente, Natalia, Minguela, Alfredo, Muro, Manuel, Parrado, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434181/ https://www.ncbi.nlm.nih.gov/pubmed/30963125 http://dx.doi.org/10.1016/j.heliyon.2019.e01391

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