Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance

Novelty and Impact Statement: Our findings suggest that soluble folate receptor (sFR) could be used in both the initial diagnosis and surveillance of patients with ovarian cancer. Our cohort constitutes one of the largest comparison groups for sFR analyzed so far. We have defined the background leve...

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Autores principales: Farran, Batoul, Albayrak, Samet, Abrams, Judith, Tainsky, Michael A., Levin, Nancy K., Morris, Robert, Matherly, Larry H., Ratnam, Manohar, Winer, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Clinical Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434204/
https://www.ncbi.nlm.nih.gov/pubmed/30761774
http://dx.doi.org/10.1002/cam4.1944
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author Farran, Batoul
Albayrak, Samet
Abrams, Judith
Tainsky, Michael A.
Levin, Nancy K.
Morris, Robert
Matherly, Larry H.
Ratnam, Manohar
Winer, Ira
author_facet Farran, Batoul
Albayrak, Samet
Abrams, Judith
Tainsky, Michael A.
Levin, Nancy K.
Morris, Robert
Matherly, Larry H.
Ratnam, Manohar
Winer, Ira
author_sort Farran, Batoul
collection PubMed
description Novelty and Impact Statement: Our findings suggest that soluble folate receptor (sFR) could be used in both the initial diagnosis and surveillance of patients with ovarian cancer. Our cohort constitutes one of the largest comparison groups for sFR analyzed so far. We have defined the background level of sFR using healthy volunteers. This is also the first study to prospectively follow patients in the surveillance setting to concurrently identify differential changes in tumor markers CA‐125 and sFR.
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spelling pubmed-64342042019-04-15 Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance Farran, Batoul Albayrak, Samet Abrams, Judith Tainsky, Michael A. Levin, Nancy K. Morris, Robert Matherly, Larry H. Ratnam, Manohar Winer, Ira Cancer Med Clinical Cancer Research Novelty and Impact Statement: Our findings suggest that soluble folate receptor (sFR) could be used in both the initial diagnosis and surveillance of patients with ovarian cancer. Our cohort constitutes one of the largest comparison groups for sFR analyzed so far. We have defined the background level of sFR using healthy volunteers. This is also the first study to prospectively follow patients in the surveillance setting to concurrently identify differential changes in tumor markers CA‐125 and sFR. John Wiley and Sons Inc. 2019-02-13 /pmc/articles/PMC6434204/ /pubmed/30761774 http://dx.doi.org/10.1002/cam4.1944 Text en © 2019 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Cancer Research
Farran, Batoul
Albayrak, Samet
Abrams, Judith
Tainsky, Michael A.
Levin, Nancy K.
Morris, Robert
Matherly, Larry H.
Ratnam, Manohar
Winer, Ira
Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance
title Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance
title_full Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance
title_fullStr Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance
title_full_unstemmed Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance
title_short Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance
title_sort serum folate receptor α (sfr) in ovarian cancer diagnosis and surveillance
topic Clinical Cancer Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434204/
https://www.ncbi.nlm.nih.gov/pubmed/30761774
http://dx.doi.org/10.1002/cam4.1944
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