Cargando…

Proteasome inhibitor MG132 inhibits the process of renal interstitial fibrosis

The proteasome inhibitor pathway serves a crucial role in cell cycle progression and apoptosis, and in the activation of transcription factors and cytokines in tumor cells. The aim of the current study was to investigate the effect of the proteasome inhibitor, MG132, on transforming growth factor (T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Lin, Zhu, Bingbing, Chen, Hui, Jin, Yuanmeng, Liu, Jian, Wang, Weiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434245/ https://www.ncbi.nlm.nih.gov/pubmed/30936965 http://dx.doi.org/10.3892/etm.2019.7329

Ejemplares similares

The proteasomal inhibitor MG132 prevents muscular dystrophy in zebrafish
por: Winder, Steve J, et al.
Publicado: (2011)

Proteasome inhibitor MG-132 induces MCPIP1 expression
por: Skalniak, Lukasz, et al.
Publicado: (2013)

Effects of proteasome inhibitor MG-132 on the parasite Schistosoma mansoni
por: Morais, Enyara R., et al.
Publicado: (2017)

Systemic Perturbation of the ERK Signaling Pathway by the Proteasome Inhibitor, MG132
por: Cirit, Murat, et al.
Publicado: (2012)

MG-132, an inhibitor of proteasomes and calpains, induced inhibition of oocyte maturation and aneuploidy in mouse oocytes
por: Mailhes, John B, et al.
Publicado: (2002)

Stability of Zinc Finger Nuclease Protein Is Enhanced by the Proteasome Inhibitor MG132
por: Ramakrishna, Suresh, et al.
Publicado: (2013)

The Proteasome Inhibitor, MG132, Attenuates Diabetic Nephropathy by Inhibiting SnoN Degradation In Vivo and In Vitro
por: Huang, Wei, et al.
Publicado: (2014)

Proteasome Inhibitor MG132 Enhances Cisplatin-Induced Apoptosis in Osteosarcoma Cells and Inhibits Tumor Growth
por: Sun, Farui, et al.
Publicado: (2018)

MG132-mediated inhibition of the ubiquitin–proteasome pathway ameliorates cancer cachexia
por: Zhang, Liuping, et al.
Publicado: (2013)

The proteasome inhibitor MG132 reduces immobilization-induced skeletal muscle atrophy in mice
por: Caron, Annabelle Z, et al.
Publicado: (2011)

Transcriptional Upregulation of Plasminogen Activator Inhibitor-1 in Rat Primary Astrocytes by a Proteasomal Inhibitor MG132
por: Cho, Kyu Suk, et al.
Publicado: (2013)

Proteasome inhibitor MG132 inhibits the proliferation and promotes the cisplatin-induced apoptosis of human esophageal squamous cell carcinoma cells
por: DANG, LIFENG, et al.
Publicado: (2014)

MCPIP1 contributes to the toxicity of proteasome inhibitor MG-132 in HeLa cells by the inhibition of NF-κB
por: Skalniak, Lukasz, et al.
Publicado: (2014)

Modulatory effect of MG-132 proteasomal inhibition on boar sperm motility during in vitro capacitation
por: Hackerova, Lenka, et al.
Publicado: (2023)

Systemic Analysis of Heat Shock Response Induced by Heat Shock and a Proteasome Inhibitor MG132
por: Kim, Hee-Jung, et al.
Publicado: (2011)

Prolonged treatment with the proteasome inhibitor MG-132 induces apoptosis in PC12 rat pheochromocytoma cells
por: Tarjányi, Oktávia, et al.
Publicado: (2022)

Proteasome Inhibitor MG132 is Toxic and Inhibits the Proliferation of Rat Neural Stem Cells but Increases BDNF Expression to Protect Neurons
por: Kim, Young Min, et al.
Publicado: (2020)

Proteomic Analysis of MG132-Treated Germinating Pollen Reveals Expression Signatures Associated with Proteasome Inhibition
por: Vannini, Candida, et al.
Publicado: (2014)

Enhanced efficacy against cervical carcinomas through polymeric micelles physically incorporating the proteasome inhibitor MG132
por: Matsumoto, Yoko, et al.
Publicado: (2016)

Proteasome inhibitor MG132 suppresses pancreatic ductal adenocarcinoma-cell migration by increasing ESE3 expression
por: Jin, Fanjie, et al.
Publicado: (2020)

Effect of addition of FSH, LH and proteasome inhibitor MG132 to in vitro maturation medium on the developmental competence of yak (Bos grunniens) oocytes
por: Xiao, Xiao, et al.
Publicado: (2014)

Blocking Plasmodium falciparum Development via Dual Inhibition of Hemoglobin Degradation and the Ubiquitin Proteasome System by MG132
por: Prasad, Rajesh, et al.
Publicado: (2013)

Interplay of Autophagy Inducer Rapamycin and Proteasome Inhibitor MG132 in Reduction of Foam Cell Formation and Inflammatory Cytokine Expression
por: Zhang, Wei, et al.
Publicado: (2018)

Treatment with the Proteasome Inhibitor MG132 during the End of Oocyte Maturation Improves Oocyte Competence for Development after Fertilization in Cattle
por: You, Jinyoung, et al.
Publicado: (2012)

The Protective Effects of Protease Inhibitor MG-132 on Sepsis-Induced Acute Lung Rats and Its Possible Mechanisms
por: Wu, Bingbing, et al.
Publicado: (2019)

The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism
por: Pajonk, Frank, et al.
Publicado: (2005)

MG132, a proteasome inhibitor, induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion
por: PARK, WOO HYUN, et al.
Publicado: (2012)

Impact of High Glucose and Proteasome Inhibitor MG132 on Histone H2A and H2B Ubiquitination in Rat Glomerular Mesangial Cells
por: Gao, Chenlin, et al.
Publicado: (2013)

Renal Interstitial Fibrosis and Angiotensin Inhibition
por: Koo, Ja Wook
Publicado: (2006)

Up-regulation of the DR5 Expression by Proteasome Inhibitor MG132 Augments TRAIL-Induced Apoptosis in Soft Tissue Sarcoma Cell Lines
por: Cheong, Hee-Jeong, et al.
Publicado: (2011)

Proteasome inhibitor MG132 enhances the sensitivity of human OSCC cells to cisplatin via a ROS/DNA damage/p53 axis
por: Zheng, Zheng, et al.
Publicado: (2023)

Proteasome inhibitor (MG132) rescues Na(v)1.5 protein content and the cardiac sodium current in dystrophin-deficient mdx(5cv) mice
por: Rougier, Jean-Sébastien, et al.
Publicado: (2013)

The anti-tumor effect of proteasome inhibitor MG132 for human adenoid cystic carcinoma: correlate with the emerging role of Nrf2/Keap1 signaling pathway
por: Xu, Jiazhi, et al.
Publicado: (2022)

MG132 protects against renal dysfunction by regulating Akt-mediated inflammation in diabetic nephropathy
por: Zeng, Wei, et al.
Publicado: (2019)

Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling
por: Zhang, Yunjing, et al.
Publicado: (2018)

Polo-Like Kinase 2 Plays an Essential Role in Cytoprotection against MG132-Induced Proteasome Inhibition via Phosphorylation of Serine 19 in HSPB5
por: Ueda, Shuji, et al.
Publicado: (2022)

Sensitization of U937 leukemia cells to doxorubicin by the MG132 proteasome inhibitor induces an increase in apoptosis by suppressing NF-kappa B and mitochondrial membrane potential loss
por: Ortiz-Lazareno, Pablo César, et al.
Publicado: (2014)

Fluorofenidone inhibits apoptosis of renal tubular epithelial cells in rats with renal interstitial fibrosis
por: Yang, Hui, et al.
Publicado: (2019)

miR-212 promotes renal interstitial fibrosis by inhibiting hypoxia-inducible factor 1-α inhibitor
por: Zhang, Yun, et al.
Publicado: (2021)

Src inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis
por: Yan, Yanli, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_jandu3hu757ebogqbhlkem1dv7