Notch Inhibition Promotes Differentiation of Liver Progenitor Cells into Hepatocytes via sox9b Repression in Zebrafish

Liver regeneration after most forms of injury is mediated through the proliferation of hepatocytes. However, when hepatocyte proliferation is impaired, such as during chronic liver disease, liver progenitor cells (LPCs) arising from the biliary epithelial cell (BEC) compartment can give rise to hepa...

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Detalles Bibliográficos
Autores principales: Russell, Jacquelyn O., Ko, Sungjin, Monga, Satdarshan P., Shin, Donghun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434270/
https://www.ncbi.nlm.nih.gov/pubmed/30992706
http://dx.doi.org/10.1155/2019/8451282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434270/
https://www.ncbi.nlm.nih.gov/pubmed/30992706
http://dx.doi.org/10.1155/2019/8451282

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