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Notch Inhibition Promotes Differentiation of Liver Progenitor Cells into Hepatocytes via sox9b Repression in Zebrafish
Liver regeneration after most forms of injury is mediated through the proliferation of hepatocytes. However, when hepatocyte proliferation is impaired, such as during chronic liver disease, liver progenitor cells (LPCs) arising from the biliary epithelial cell (BEC) compartment can give rise to hepa...
Autores principales: | Russell, Jacquelyn O., Ko, Sungjin, Monga, Satdarshan P., Shin, Donghun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434270/ https://www.ncbi.nlm.nih.gov/pubmed/30992706 http://dx.doi.org/10.1155/2019/8451282 |
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