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Overexpression of ubiquitin-specific peptidase 15 in systemic sclerosis fibroblasts increases response to transforming growth factor β

OBJECTIVE: Ubiquitination of proteins leads to their degradation by the proteasome, and is regulated by ubiquitin ligases and substrate-specific ubiquitin-specific peptidases (USPs). The ubiquitination process also plays important roles in the regulation of cell metabolism and cell cycle. Here, we f...

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Detalles Bibliográficos
Autores principales:	Galant, Christine, Marchandise, Joel, Stoenoiu, Maria S, Ducreux, Julie, De Groof, Aurélie, Pirenne, Sophie, Van den Eynde, Benoit, Houssiau, Frédéric A, Lauwerys, Bernard R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Basic and Translational Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434377/ https://www.ncbi.nlm.nih.gov/pubmed/30608617 http://dx.doi.org/10.1093/rheumatology/key401

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