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Wharton’s Jelly Mesenchymal Stromal Cells Support the Expansion of Cord Blood–derived CD34(+) Cells Mimicking a Hematopoietic Niche in a Direct Cell–cell Contact Culture System

Wharton’s jelly mesenchymal stromal cells (WJ-MSCs) have been recently exploited as a feeder layer in coculture systems to expand umbilical cord blood–hematopoietic stem/progenitor cells (UCB-HSPCs). Here, we investigated the role of WJ-MSCs in supporting ex vivo UCB-HSPC expansion either when cultu...

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Detalles Bibliográficos
Autores principales: Lo Iacono, Melania, Russo, Eleonora, Anzalone, Rita, Baiamonte, Elena, Alberti, Giusi, Gerbino, Aldo, Maggio, Aurelio, La Rocca, Giampiero, Acuto, Santina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434478/
https://www.ncbi.nlm.nih.gov/pubmed/29562783
http://dx.doi.org/10.1177/0963689717737089

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