Extracellular Vesicles Derived from Wharton’s Jelly Mesenchymal Stem Cells Prevent and Resolve Programmed Cell Death Mediated by Perinatal Hypoxia-Ischemia in Neuronal Cells

Hypoxic-ischemic (HI) insult in the perinatal phase harbors a high risk of encephalopathy in the neonate. Brain cells undergo apoptosis, initiating neurodegeneration. So far, therapeutic approaches such as cooling remain limited. Transplantation of mesenchymal stem cells (MSCs) exhibits therapeutic...

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Detalles Bibliográficos
Autores principales: Joerger-Messerli, Marianne S., Oppliger, Byron, Spinelli, Marialuigia, Thomi, Gierin, di Salvo, Ivana, Schneider, Philipp, Schoeberlein, Andreina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434490/
https://www.ncbi.nlm.nih.gov/pubmed/29562785
http://dx.doi.org/10.1177/0963689717738256

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