Identification of an iron-responsive subtype in two children diagnosed with relapsing-remitting multiple sclerosis using whole exome sequencing

BACKGROUND: Multiple sclerosis is a disorder related to demyelination of axons. Iron is an essential cofactor in myelin synthesis. Previously, we described two children (males of mixed ancestry) with relapsing-remitting multiple sclerosis (RRMS) where long-term remission was achieved by regular iron...

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Detalles Bibliográficos
Autores principales: van Rensburg, Susan J., Peeters, Armand V., van Toorn, Ronald, Schoeman, Johan, Moremi, Kelebogile E., van Heerden, Carel J., Kotze, Maritha J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434495/
https://www.ncbi.nlm.nih.gov/pubmed/30963028
http://dx.doi.org/10.1016/j.ymgmr.2019.100465

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