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MRI and Bone Scintigraphy for Breast Cancer Bone Metastase: A Meta-analysis
OBJECTIVE: The aim of this study was to compare the diagnostic value of magnetic resonance image (MRI) and bone scintigraphy (BS) in the diagnosis of breast cancer bone metastases. METHODS: Searching in the databases including PubMed, Embase about the comparative study of MRI and bone scintigraphy i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434664/ https://www.ncbi.nlm.nih.gov/pubmed/30931397 http://dx.doi.org/10.1515/med-2019-0029 |
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author | Rong, Yue Ren, Hong Ding, Xianjun |
author_facet | Rong, Yue Ren, Hong Ding, Xianjun |
author_sort | Rong, Yue |
collection | PubMed |
description | OBJECTIVE: The aim of this study was to compare the diagnostic value of magnetic resonance image (MRI) and bone scintigraphy (BS) in the diagnosis of breast cancer bone metastases. METHODS: Searching in the databases including PubMed, Embase about the comparative study of MRI and bone scintigraphy in the diagnosis of breast cancer bone metastases during 2000~2018. After we screened further, the extracted effective data were calculated by Meta-Disc 1.4 software. RESULTS: We obtained 4 articles. The pooled estimates for sensitivity of MRI, BS were 0.99 (95% CI, [0.95, 1.00]) and 0.93 (95% CI, [0.88, 0.97]) respectively; For specificity were 0.99 (95% CI, [0.95, 1.00]) and 0.86 (95% CI, [0.79, 0.92]) respectively. The AUC of SROC curve for MRI and BS were 0.9948 and 0.9675 respectively. CONCLUSION: MRI remains to be a satisfactory method for the diagnosis of breast cancer bone metastases and should first be considered for patients. |
format | Online Article Text |
id | pubmed-6434664 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | De Gruyter |
record_format | MEDLINE/PubMed |
spelling | pubmed-64346642019-03-29 MRI and Bone Scintigraphy for Breast Cancer Bone Metastase: A Meta-analysis Rong, Yue Ren, Hong Ding, Xianjun Open Med (Wars) Research Article OBJECTIVE: The aim of this study was to compare the diagnostic value of magnetic resonance image (MRI) and bone scintigraphy (BS) in the diagnosis of breast cancer bone metastases. METHODS: Searching in the databases including PubMed, Embase about the comparative study of MRI and bone scintigraphy in the diagnosis of breast cancer bone metastases during 2000~2018. After we screened further, the extracted effective data were calculated by Meta-Disc 1.4 software. RESULTS: We obtained 4 articles. The pooled estimates for sensitivity of MRI, BS were 0.99 (95% CI, [0.95, 1.00]) and 0.93 (95% CI, [0.88, 0.97]) respectively; For specificity were 0.99 (95% CI, [0.95, 1.00]) and 0.86 (95% CI, [0.79, 0.92]) respectively. The AUC of SROC curve for MRI and BS were 0.9948 and 0.9675 respectively. CONCLUSION: MRI remains to be a satisfactory method for the diagnosis of breast cancer bone metastases and should first be considered for patients. De Gruyter 2019-03-13 /pmc/articles/PMC6434664/ /pubmed/30931397 http://dx.doi.org/10.1515/med-2019-0029 Text en © 2019 Yue Rong et al. published by De Gruyter http://creativecommons.org/licenses/by-nc-nd/4.0 This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. |
spellingShingle | Research Article Rong, Yue Ren, Hong Ding, Xianjun MRI and Bone Scintigraphy for Breast Cancer Bone Metastase: A Meta-analysis |
title | MRI and Bone Scintigraphy for Breast Cancer Bone Metastase: A Meta-analysis |
title_full | MRI and Bone Scintigraphy for Breast Cancer Bone Metastase: A Meta-analysis |
title_fullStr | MRI and Bone Scintigraphy for Breast Cancer Bone Metastase: A Meta-analysis |
title_full_unstemmed | MRI and Bone Scintigraphy for Breast Cancer Bone Metastase: A Meta-analysis |
title_short | MRI and Bone Scintigraphy for Breast Cancer Bone Metastase: A Meta-analysis |
title_sort | mri and bone scintigraphy for breast cancer bone metastase: a meta-analysis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434664/ https://www.ncbi.nlm.nih.gov/pubmed/30931397 http://dx.doi.org/10.1515/med-2019-0029 |
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