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UNBS5162 and amonafide inhibits tumor progression in human melanoma by the AKT/mTOR pathway
BACKGROUND: Human melanoma is a malignant tumor originated from melanocytes with high invasion, metastasis, and poor prognosis. In this study, the effects of naphthalimides UNBS5162 and amonafide on the properties of proliferation and apoptosis in human melanoma cells were confirmed. METHODS: Cell p...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434921/ https://www.ncbi.nlm.nih.gov/pubmed/30962721 http://dx.doi.org/10.2147/CMAR.S177623 |