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Location-dependent maintenance of intrinsic susceptibility to mTORC1-driven tumorigenesis
Neural stem/progenitor cells (NSPCs) of the ventricular–subventricular zone (V-SVZ) are candidate cells of origin for many brain tumors. However, whether NSPCs in different locations within the V-SVZ differ in susceptibility to tumorigenic mutations is unknown. Here, single-cell measurements of sign...
Autores principales: | Rushing, Gabrielle V, Brockman, Asa A, Bollig, Madelyn K, Leelatian, Nalin, Mobley, Bret C, Irish, Jonathan M, Ess, Kevin C, Fu, Cary, Ihrie, Rebecca A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435042/ https://www.ncbi.nlm.nih.gov/pubmed/30910807 http://dx.doi.org/10.26508/lsa.201800218 |
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