Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma

The immune system employs several checkpoint pathways to regulate responses, maintain homeostasis and prevent self-reactivity and autoimmunity. Tumor cells can hijack these protective mechanisms to enable immune escape, cancer survival and proliferation. Blocking antibodies, designed to interfere wi...

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Detalles Bibliográficos
Autores principales: Khair, Duaa O., Bax, Heather J., Mele, Silvia, Crescioli, Silvia, Pellizzari, Giulia, Khiabany, Atousa, Nakamura, Mano, Harris, Robert J., French, Elise, Hoffmann, Ricarda M., Williams, Iwan P., Cheung, Anthony, Thair, Benjamin, Beales, Charlie T., Touizer, Emma, Signell, Adrian W., Tasnova, Nahrin L., Spicer, James F., Josephs, Debra H., Geh, Jenny L., MacKenzie Ross, Alastair, Healy, Ciaran, Papa, Sophie, Lacy, Katie E., Karagiannis, Sophia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435047/
https://www.ncbi.nlm.nih.gov/pubmed/30941125
http://dx.doi.org/10.3389/fimmu.2019.00453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435047/
https://www.ncbi.nlm.nih.gov/pubmed/30941125
http://dx.doi.org/10.3389/fimmu.2019.00453

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