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Bivariate mixture models for the joint distribution of repeated serum ferritin and transferrin saturation measured 12 years apart in a cohort of healthy middle-aged Australians

Homozygosity for the p.C282Y substitution in the HFE protein encoded by the hemochromatosis gene on chromosome 6p (HFE) is a common genetic trait that increases susceptibility to iron overload. McLaren et al. used bivariate mixture modeling to analyze the joint population distribution of transferrin...

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Detalles Bibliográficos
Autores principales: McLaren, Christine E., Chen, Wen-Pin, Bertalli, Nadine A., Delatycki, Martin B., Giles, Graham G., English, Dallas R., Hopper, John L., Allen, Katrina J., Gurrin, Lyle C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435128/
https://www.ncbi.nlm.nih.gov/pubmed/30913256
http://dx.doi.org/10.1371/journal.pone.0214196