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Bivariate mixture models for the joint distribution of repeated serum ferritin and transferrin saturation measured 12 years apart in a cohort of healthy middle-aged Australians
Homozygosity for the p.C282Y substitution in the HFE protein encoded by the hemochromatosis gene on chromosome 6p (HFE) is a common genetic trait that increases susceptibility to iron overload. McLaren et al. used bivariate mixture modeling to analyze the joint population distribution of transferrin...
Autores principales: | McLaren, Christine E., Chen, Wen-Pin, Bertalli, Nadine A., Delatycki, Martin B., Giles, Graham G., English, Dallas R., Hopper, John L., Allen, Katrina J., Gurrin, Lyle C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435128/ https://www.ncbi.nlm.nih.gov/pubmed/30913256 http://dx.doi.org/10.1371/journal.pone.0214196 |
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