Initiation-specific alleles of the Cdc45 helicase-activating protein

The committed step in DNA replication initiation is the activation of the Mcm2-7 replicative DNA helicase. Two activators, Cdc45 and GINS, associate with Mcm2-7 at origins of replication to form the CMG complex, which is the active eukaryotic replicative helicase. These activators function during bo...

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Detalles Bibliográficos
Autores principales: Rios-Morales, Ramon Y., Chan, Sze Ham, Bell, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435160/
https://www.ncbi.nlm.nih.gov/pubmed/30913274
http://dx.doi.org/10.1371/journal.pone.0214426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435160/
https://www.ncbi.nlm.nih.gov/pubmed/30913274
http://dx.doi.org/10.1371/journal.pone.0214426

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