Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation

Branched chain amino acids (BCAA) are essential elements of the human diet, which display increased plasma levels in obesity and regained particular interest as potential biomarkers for development of diabetes. To define determinants of insulin resistance (IR) we investigated 73 genes involved in BC...

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Detalles Bibliográficos
Autores principales: Haydar, Sara, Grigorescu, Florin, Vintilă, Mădălina, Cogne, Yannick, Lautier, Corinne, Tutuncu, Yildiz, Brun, Jean Frederic, Robine, Jean Marie, Pugeat, Michel, Normand, Christophe, Poucheret, Patrick, Gheorghiu, Monica Livia, Georgescu, Carmen, Badiu, Corin, Băculescu, Nicoleta, Renard, Eric, Ylli, Dorina, Badiou, Stephanie, Sutra, Thibault, Cristol, Jean Paul, Mercier, Jacques, Gomis, Ramon, Macias, Josep Maria, Litvinov, Serghey, Khusnutdinova, Elza, Poiana, Catalina, Pasquali, Renato, Lauro, Davide, Sesti, Giorgio, Prudente, Sabrina, Trischitta, Vincenzo, Tsatsoulis, Agathocles, Abdelhak, Sonia, Barakat, Abdelhamid, Zenati, Akila, Ylli, Agron, Satman, Ilhan, Kanninen, Timo, Rinato, Yves, Missoni, Sasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435171/
https://www.ncbi.nlm.nih.gov/pubmed/30913280
http://dx.doi.org/10.1371/journal.pone.0214122

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