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Modulation of peripheral blood immune cells by early use of steroids and its association with clinical outcomes in patients with metastatic non-small cell lung cancer treated with immune checkpoint inhibitors

BACKGROUND: Steroids are frequently used in patients with metastatic non-small cell lung cancer (mNSCLC), but they could be detrimental for patients treated with immune checkpoint inhibitors (ICIs). Here, we assessed the association between early use of steroids, clinical outcomes and peripheral imm...

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Detalles Bibliográficos
Autores principales: Fucà, Giovanni, Galli, Giulia, Poggi, Marta, Lo Russo, Giuseppe, Proto, Claudia, Imbimbo, Martina, Ferrara, Roberto, Zilembo, Nicoletta, Ganzinelli, Monica, Sica, Antonio, Torri, Valter, Colombo, Mario Paolo, Vernieri, Claudio, Balsari, Andrea, de Braud, Filippo, Garassino, Marina Chiara, Signorelli, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435242/
https://www.ncbi.nlm.nih.gov/pubmed/30964126
http://dx.doi.org/10.1136/esmoopen-2018-000457