A potently neutralizing human monoclonal antibody targeting an epitope in the West Nile virus E protein preferentially recognizes mature virions

West Nile virus (WNV), a member of the Flavivirus genus, is a leading cause of viral encephalitis in the United States(1). The development of neutralizing antibodies against the flavivirus envelope (E) protein is critical for immunity and vaccine protection(2). Previously identified candidate therap...

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Detalles Bibliográficos
Autores principales: Goo, Leslie, Debbink, Kari, Kose, Nurgun, Sapparapu, Gopal, Doyle, Michael P., Wessel, Alex W., Richner, Justin M., Burgomaster, Katherine E., Larman, Bridget C., Dowd, Kimberly A., Diamond, Michael S., Crowe, James E., Pierson, Theodore C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435290/
https://www.ncbi.nlm.nih.gov/pubmed/30455471
http://dx.doi.org/10.1038/s41564-018-0283-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435290/
https://www.ncbi.nlm.nih.gov/pubmed/30455471
http://dx.doi.org/10.1038/s41564-018-0283-7

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