Cargando…
A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion
Aberrant display of the truncated core1 O-glycan T-antigen is a common feature of human cancer cells that correlates with metastasis. Here we show that T-antigen in Drosophila melanogaster macrophages is involved in their developmentally programmed tissue invasion. Higher macrophage T-antigen levels...
Autores principales: | Valoskova, Katarina, Biebl, Julia, Roblek, Marko, Emtenani, Shamsi, Gyoergy, Attila, Misova, Michaela, Ratheesh, Aparna, Reis-Rodrigues, Patricia, Shkarina, Kateryna, Larsen, Ida Signe Bohse, Vakhrushev, Sergey Y, Clausen, Henrik, Siekhaus, Daria E |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435326/ https://www.ncbi.nlm.nih.gov/pubmed/30910009 http://dx.doi.org/10.7554/eLife.41801 |
Ejemplares similares
-
Tools Allowing Independent Visualization and Genetic Manipulation of Drosophila melanogaster Macrophages and Surrounding Tissues
por: Gyoergy, Attila, et al.
Publicado: (2018) -
Fos regulates macrophage infiltration against surrounding tissue resistance by a cortical actin-based mechanism in Drosophila
por: Belyaeva, Vera, et al.
Publicado: (2022) -
Macrophage mitochondrial bioenergetics and tissue invasion are boosted by an Atossa‐Porthos axis in Drosophila
por: Emtenani, Shamsi, et al.
Publicado: (2022) -
The Heterotaxy gene, GALNT11, glycosylates Notch to orchestrate cilia type and laterality
por: Boskovski, Marko T., et al.
Publicado: (2013) -
Optogenetic Induction of Pyroptosis, Necroptosis, and Apoptosis in Mammalian Cell Lines
por: Shkarina, Kateryna, et al.
Publicado: (2023)