Cargando…

SREBP-1c as a molecular bridge between lipogenesis and cell cycle progression of clear cell renal carcinoma

Sterol regulatory element binding protein 1c (SREBP-1c) promotes lipogenesis and tumor growth in various cancers. It is well known that clear cell renal cell carcinoma (ccRCC), a major subtype of the kidney cancers, exhibits elevated lipid accumulation. However, it has not been fully understood how...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sethi, Gautam, Shanmugam, Muthu K., Kumar, Alan Prem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2017
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435460/ https://www.ncbi.nlm.nih.gov/pubmed/29138263 http://dx.doi.org/10.1042/BSR20171270

Ejemplares similares

Role of RNF20 in cancer development and progression – a comprehensive review
por: Sethi, Gautam, et al.
Publicado: (2018)

Nifedipine Modulates Renal Lipogenesis via the AMPK-SREBP Transcriptional Pathway
por: Lin, Yen-Chung, et al.
Publicado: (2019)

Targeting SREBP-1-Mediated Lipogenesis as Potential Strategies for Cancer
por: Zhao, Qiushi, et al.
Publicado: (2022)

Cdk8 attenuates lipogenesis by inhibiting SREBP-dependent transcription in Drosophila
por: Li, Xiao, et al.
Publicado: (2022)

MicroRNA-196a promotes renal cancer cell migration and invasion by targeting BRAM1 to regulate SMAD and MAPK signaling pathways
por: Cui, Jianzhou, et al.
Publicado: (2021)

Interplay of PKD3 with SREBP1 Promotes Cell Growth via Upregulating Lipogenesis in Prostate Cancer Cells
por: Li, Ling, et al.
Publicado: (2019)

The interplay of transcriptional coregulator NUPR1 with SREBP1 promotes hepatocellular carcinoma progression via upregulation of lipogenesis
por: Wang, Yongjia, et al.
Publicado: (2022)

Oncogenic signaling upstream of mTORC1 drives lipogenesis and proliferation through SREBP
por: Ricoult, Stéphane, et al.
Publicado: (2014)

GPX8 regulates clear cell renal cell carcinoma tumorigenesis through promoting lipogenesis by NNMT
por: Nguyen, Tin Tin Manh, et al.
Publicado: (2023)

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy
por: Talebi, Ali, et al.
Publicado: (2018)

Ammonia stimulates SCAP/Insig dissociation and SREBP-1 activation to promote lipogenesis and tumor growth
por: Cheng, Chunming, et al.
Publicado: (2022)

Dihydrotestosterone induces SREBP-1 expression and lipogenesis through the phosphoinositide 3-kinase/Akt pathway in HaCaT cells
por: Zhou, Bing-rong, et al.
Publicado: (2012)

Histone Deacetylase 1 Reduces Lipogenesis by Suppressing SREBP1 Transcription in Human Sebocyte Cell Line SZ95
por: Shin, Hye Sun, et al.
Publicado: (2021)

Pro-Apoptotic and Anti-Cancer Properties of Diosgenin: A Comprehensive and Critical Review
por: Sethi, Gautam, et al.
Publicado: (2018)

Ursolic Acid Inhibits the Initiation, Progression of Prostate Cancer and Prolongs the Survival of TRAMP Mice by Modulating Pro-Inflammatory Pathways
por: Shanmugam, Muthu K., et al.
Publicado: (2012)

Metformin targets Clusterin to control lipogenesis and inhibit the growth of bladder cancer cells through SREBP-1c/FASN axis
por: Deng, Jun, et al.
Publicado: (2021)

Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice
por: Linden, Albert G., et al.
Publicado: (2018)

Lycium barbarum glycopeptide targets PER2 to inhibit lipogenesis in glioblastoma by downregulating SREBP1c
por: Yao, Jian, et al.
Publicado: (2023)

MBTPS2 acts as a regulator of lipogenesis and cholesterol synthesis through SREBP signalling in prostate cancer
por: Tibbo, Amy J., et al.
Publicado: (2023)

RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression
por: Guo, Di, et al.
Publicado: (2019)

An AKT/PRMT5/SREBP1 axis in lung adenocarcinoma regulates de novo lipogenesis and tumor growth
por: Liu, Liu, et al.
Publicado: (2021)

NRF3 upregulates gene expression in SREBP2-dependent mevalonate pathway with cholesterol uptake and lipogenesis inhibition
por: Waku, Tsuyoshi, et al.
Publicado: (2021)

CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing
por: Zeng, Han, et al.
Publicado: (2021)

A novel small compound TOIDC suppresses lipogenesis via SREBP1-dependent signaling to curb MAFLD
por: Shao, Yaodi, et al.
Publicado: (2022)

Correction to: Lycium barbarum glycopeptide targets PER2 to inhibit lipogenesis in glioblastoma by downregulating SREBP1c
por: Yao, Jian, et al.
Publicado: (2023)

α‐Mangostin suppresses the de novo lipogenesis and enhances the chemotherapeutic response to gemcitabine in gallbladder carcinoma cells via targeting the AMPK/SREBP1 cascades
por: Shi, Yu, et al.
Publicado: (2019)

The Role of Resveratrol in Cancer Therapy
por: Ko, Jeong-Hyeon, et al.
Publicado: (2017)

Evidence for the Involvement of the Master Transcription Factor NF-κB in Cancer Initiation and Progression
por: Puar, Yu Rou, et al.
Publicado: (2018)

Clear cell adenocarcinoma of urinary bladder: A case report and review
por: Sethi, Somika, et al.
Publicado: (2011)

Novel 1,3,4-Oxadiazole Induces Anticancer Activity by Targeting NF-κB in Hepatocellular Carcinoma Cells
por: Mohan, Chakrabhavi Dhananjaya, et al.
Publicado: (2018)

Nifedipine Exacerbates Lipogenesis in the Kidney via KIM-1, CD36, and SREBP Upregulation: Implications from an Animal Model for Human Study
por: Lin, Yen-Chung, et al.
Publicado: (2020)

Lipidomics reveals that sustained SREBP-1-dependent lipogenesis is a key mediator of gefitinib-acquired resistance in EGFR-mutant lung cancer
por: Xu, Chuncao, et al.
Publicado: (2021)

Lipid-cell cycle nexus: SREBP regulates microRNAs targeting Fbxw7
por: Esquejo, Ryan M, et al.
Publicado: (2014)

LXRɑ participates in the mTOR/S6K1/SREBP-1c signaling pathway during sodium palmitate-induced lipogenesis in HepG2 cells
por: Zhou, Youping, et al.
Publicado: (2018)

The lncRNA ZFAS1 regulates lipogenesis in colorectal cancer by binding polyadenylate-binding protein 2 to stabilize SREBP1 mRNA
por: Wang, Huishan, et al.
Publicado: (2021)

LncCCAT1 interaction protein PKM2 upregulates SREBP2 phosphorylation to promote osteosarcoma tumorigenesis by enhancing the Warburg effect and lipogenesis
por: Pu, Feifei, et al.
Publicado: (2022)

Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice
por: Yenilmez, Batuhan, et al.
Publicado: (2022)

Activation of sterol regulatory element‐binding protein 1 (SREBP1)‐mediated lipogenesis by the Epstein–Barr virus‐encoded latent membrane protein 1 (LMP1) promotes cell proliferation and progression of nasopharyngeal carcinoma
por: Lo, Angela Kwok‐Fung, et al.
Publicado: (2018)

COMPREHENSIVE MOLECULAR CHARACTERIZATION OF CLEAR CELL RENAL CELL CARCINOMA
Publicado: (2013)

Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells
por: Yang, Nian, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_asjej4cr177o5dsl2143o0qq9e