Insulin degrading enzyme contributes to the pathology in a mixed model of Type 2 diabetes and Alzheimer’s disease: possible mechanisms of IDE in T2D and AD

Insulin degrading enzyme (IDE) is believed to act as a junction point of Type 2 diabetes (T2D) and Alzheimer's disease (AD); however, the underlying mechanism was not completely clear yet. Transgenic APPSwe/PS1 mice were used as the AD model and were treated with streptozocin/streptozotocin (ST...

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Detalles Bibliográficos
Autores principales: Li, Huajie, Wu, Jian, Zhu, Linfeng, Sha, Luolin, Yang, Song, Wei, Jiang, Ji, Lei, Tang, Xiaochun, Mao, Keshi, Cao, Liping, Wei, Ning, Xie, Wei, Yang, Zhilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435468/
https://www.ncbi.nlm.nih.gov/pubmed/29222348
http://dx.doi.org/10.1042/BSR20170862

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