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Vitamin D-induced vitamin D receptor expression induces tamoxifen sensitivity in MCF-7 stem cells via suppression of Wnt/β-catenin signaling

Objective: Cancer stem cells (CSCs) are responsible for the drug resistance of breast cancers. Vitamin D deficiency promotes tumor resistance. The present study examined the effect of vitamin D and vitamin D receptor (VDR) expression on the tamoxifen resistance of CSCs. Methods: MCF-7 cells were tre...

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Detalles Bibliográficos
Autores principales:	Zheng, Wei, Duan, Bofeng, Zhang, Qian, Ouyang, Linna, Peng, Wei, Qian, Fuyong, Wang, Yibin, Huang, Shiting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435469/ https://www.ncbi.nlm.nih.gov/pubmed/30314996 http://dx.doi.org/10.1042/BSR20180595

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