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Lysosomal Pathways and Autophagy Distinctively Control Endothelial Cell Behavior to Affect Tumor Vasculature
Cancer cell-stromal cell crosstalk is orchestrated by a plethora of ligand-receptor interactions generating a tumor microenvironment (TME) which favors tumor growth. The high pro-angiogenic nature of the TME perpetuates the chaotic network of structurally immature, low pericyte-covered vessels chara...
Autores principales: | Schaaf, Marco B., Houbaert, Diede, Meçe, Odeta, To, San Kit, Ganne, Maarten, Maes, Hannelore, Agostinis, Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435524/ https://www.ncbi.nlm.nih.gov/pubmed/30949450 http://dx.doi.org/10.3389/fonc.2019.00171 |
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