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Activin A regulates the epidermal growth factor receptor promoter by activating the PI3K/SP1 pathway in oral squamous cell carcinoma cells
Epidermal growth factor receptor (EGFR) and activin A are both overexpressed in oral cavity squamous cell carcinoma (OSCC). We evaluated their clinical correlation and activin A-mediated EGFR regulation in this study. Overexpression of both transcripts/proteins indicated a poorer prognosis in OSCC p...
Autores principales: | Tsai, Chi-Neu, Tsai, Chia-Lung, Yi, Jui-Shan, Kao, Huang-Kai, Huang, Yenlin, Wang, Chun-I, Lee, Yun-Shien, Chang, Kai-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435638/ https://www.ncbi.nlm.nih.gov/pubmed/30914776 http://dx.doi.org/10.1038/s41598-019-41396-7 |
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