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Deciphering the chronology of copy number alterations in Multiple Myeloma

Multiple myeloma (MM) and its precursor condition MGUS are characterized by chromosomal aberrations. Here, we comprehensively characterize the order of occurrence of these complex genomic events underlying MM development using 500 MGUS, and MM samples. We identify hyperdiploid MM (HMM) and non-HMM a...

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Detalles Bibliográficos
Autores principales: Aktas Samur, Anil, Minvielle, Stephane, Shammas, Masood, Fulciniti, Mariateresa, Magrangeas, Florence, Richardson, Paul G., Moreau, Philippe, Attal, Michel, Anderson, Kenneth C., Parmigiani, Giovanni, Avet-Loiseau, Hervé, Munshi, Nikhil C., Samur, Mehmet Kemal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435669/
https://www.ncbi.nlm.nih.gov/pubmed/30914633
http://dx.doi.org/10.1038/s41408-019-0199-3