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The M(1) muscarinic acetylcholine receptor subtype is important for retinal neuron survival in aging mice
Muscarinic acetylcholine receptors have been implicated as potential neuroprotective targets for glaucoma. We tested the hypothesis that the lack of a single muscarinic receptor subtype leads to age-dependent neuron reduction in the retinal ganglion cell layer. Mice with targeted disruption of singl...
Autores principales: | Laspas, Panagiotis, Zhutdieva, Mayagozel B., Brochhausen, Christoph, Musayeva, Aytan, Zadeh, Jenia Kouchek, Pfeiffer, Norbert, Xia, Ning, Li, Huige, Wess, Juergen, Gericke, Adrian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435680/ https://www.ncbi.nlm.nih.gov/pubmed/30914695 http://dx.doi.org/10.1038/s41598-019-41425-5 |
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