Cargando…

The functional impact of G protein-coupled receptor 142 (Gpr142) on pancreatic β-cell in rodent

We have recently shown that the G protein-coupled receptor 142 (GPR142) is expressed in both rodent and human pancreatic β-cells. Herein, we investigated the cellular distribution of GPR142 within islets and the effects of selective agonists of GPR142 on glucose-stimulated insulin secretion (GSIS) i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Al-Amily, Israa Mohammad, Dunér, Pontus, Groop, Leif, Salehi, Albert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2019
Materias:	Signaling and Cell Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435787/ https://www.ncbi.nlm.nih.gov/pubmed/30767071 http://dx.doi.org/10.1007/s00424-019-02262-7

Ejemplares similares

Ablation of GPR56 Causes β-Cell Dysfunction by ATP Loss through Mistargeting of Mitochondrial VDAC1 to the Plasma Membrane
por: Mohammad Al-Amily, Israa, et al.
Publicado: (2023)

Pan-Cancer Analysis and Drug Formulation for GPR139 and GPR142
por: Kaushik, Aman Chandra, et al.
Publicado: (2021)

The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca(2+)-activated large-conductance K(+) channels in endothelial cells
por: Bondarenko, Alexander I., et al.
Publicado: (2010)

Frequency-dependent mitochondrial Ca(2+) accumulation regulates ATP synthesis in pancreatic β cells
por: Tarasov, Andrei I., et al.
Publicado: (2012)

G protein-coupled estrogen receptor inhibits the P2Y receptor-mediated Ca(2+) signaling pathway in human airway epithelia
por: Hao, Yuan, et al.
Publicado: (2016)

The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones
por: Rudenko, Olga, et al.
Publicado: (2018)

Fluorescent protein vectors for pancreatic islet cell identification in live-cell imaging
por: Shuai, Hongyan, et al.
Publicado: (2016)

GPR142 prompts glucagon-like Peptide-1 release from islets to improve β cell function
por: Lin, Hua V., et al.
Publicado: (2018)

The context-dependent role of the Na(+)/Ca(2+)-exchanger (NCX) in pancreatic stellate cell migration
por: Loeck, Thorsten, et al.
Publicado: (2023)

Inhibitors of Bcl-2 protein family deplete ER Ca(2+) stores in pancreatic acinar cells
por: Gerasimenko, Julia, et al.
Publicado: (2010)

Insulin downregulates the expression of the Ca(2+)-activated nonselective cation channel TRPM5 in pancreatic islets from leptin-deficient mouse models
por: Colsoul, Barbara, et al.
Publicado: (2013)

GPR142 Agonists Stimulate Glucose-Dependent Insulin Secretion via Gq-Dependent Signaling
por: Wang, Jingru, et al.
Publicado: (2016)

GPR142 Controls Tryptophan-Induced Insulin and Incretin Hormone Secretion to Improve Glucose Metabolism
por: Lin, Hua V., et al.
Publicado: (2016)

Differential role of GPR142 in tryptophan-mediated enhancement of insulin secretion in obese and lean mice
por: Ueda, Yoko, et al.
Publicado: (2018)

TGF-β1 increases permeability of ciliated airway epithelia via redistribution of claudin 3 from tight junction into cell nuclei
por: Schilpp, Carolin, et al.
Publicado: (2021)

miR-142 orchestrates a network of actin cytoskeleton regulators during megakaryopoiesis
por: Chapnik, Elik, et al.
Publicado: (2014)

Coulomb Excitation of $^{142}$Xe
por: Henrich, C, et al.
Publicado: (2018)

142nd SPSC Meeting
Publicado: (2021)

142nd LHCC Meeting
Publicado: (2020)

Lipopolysaccharide modifies amiloride-sensitive Na(+) transport processes across human airway cells: role of mitogen-activated protein kinases ERK 1/2 and 5
por: Baines, D. L., et al.
Publicado: (2009)

Measurement of the decay scheme of $^{142}$Cs
por: Jones, P; iThemba LABS
Publicado: (2020)

Minutes of the 142nd Meeting of the LHCC
por: CERN. Geneva. Large Hadron Collider Experiments Committee, et al.
Publicado: (2020)

Health Tract, No. 142: Eating Habits
Publicado: (1863)

Health Tract, No. 142: Eating Habits
Publicado: (1865)

ICR142 Benchmarker: evaluating, optimising and benchmarking variant calling performance using the ICR142 NGS validation series
por: Ruark, Elise, et al.
Publicado: (2018)

MON-603 GPR142 Expression Levels Were Correlated with Plasma Ghrelin Levels and Heights in Morbidly Obese Patients
por: Ueda, Yoko, et al.
Publicado: (2020)

Specific Activation of the G Protein-coupled Receptor BNGR-A21 by the Neuropeptide Corazonin from the Silkworm, Bombyx mori, Dually Couples to the G(q) and G(s) Signaling Cascades
por: Yang, Jingwen, et al.
Publicado: (2013)

Physiology and cell biology of acupuncture observed in calcium signaling activated by acoustic shear wave
por: Li, Geng, et al.
Publicado: (2011)

Acid-evoked Ca(2+) signalling in rat sensory neurones: effects of anoxia and aglycaemia
por: Henrich, Michael, et al.
Publicado: (2009)

H(2)O(2)-mediated modulation of cytosolic signaling and organelle function in rat hippocampus
por: Gerich, Florian J., et al.
Publicado: (2009)

Effects of exogenous hydrogen sulphide on calcium signalling, background (TASK) K channel activity and mitochondrial function in chemoreceptor cells
por: Buckler, Keith J.
Publicado: (2012)

Aldosterone does not require angiotensin II to activate NCC through a WNK4–SPAK–dependent pathway
por: van der Lubbe, Nils, et al.
Publicado: (2012)

Inhibition of HERG1 K(+) channel protein expression decreases cell proliferation of human small cell lung cancer cells
por: Glassmeier, Günter, et al.
Publicado: (2011)

Elasticity changes anti-correlate with NO production for human endothelial cells stimulated with TNF-α
por: Szczygiel, Agnieszka M., et al.
Publicado: (2011)

SIK1/SOS2 networks: decoding sodium signals via calcium-responsive protein kinase pathways
por: Bertorello, Alejandro Mario, et al.
Publicado: (2009)

ATP depletion induces translocation of STIM1 to puncta and formation of STIM1–ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP
por: Chvanov, Michael, et al.
Publicado: (2008)

RhoA-ROCK signaling is involved in contraction-mediated inhibition of SERCA2a expression in cardiomyocytes
por: Vlasblom, Ronald, et al.
Publicado: (2009)

Identification of the Ca(2+) entry pathway involved in deoxygenation-induced phosphatidylserine exposure in red blood cells from patients with sickle cell disease
por: Cytlak, U. M., et al.
Publicado: (2013)

Inhibitors of second messenger pathways and Ca(2+)-induced exposure of phosphatidylserine in red blood cells of patients with sickle cell disease
por: Gbotosho, O. T., et al.
Publicado: (2013)

Effects of IL-6 on pyruvate dehydrogenase regulation in mouse skeletal muscle
por: Biensø, Rasmus S., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_qmkb5de2ivsnvdboqu7hnsedm0