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Interfacial Stress in the Development of Biologics: Fundamental Understanding, Current Practice, and Future Perspective
Biologic products encounter various types of interfacial stress during development, manufacturing, and clinical administration. When proteins come in contact with vapor–liquid, solid–liquid, and liquid–liquid surfaces, these interfaces can significantly impact the protein drug product quality attrib...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435788/ https://www.ncbi.nlm.nih.gov/pubmed/30915582 http://dx.doi.org/10.1208/s12248-019-0312-3 |