Interfacial Stress in the Development of Biologics: Fundamental Understanding, Current Practice, and Future Perspective

Biologic products encounter various types of interfacial stress during development, manufacturing, and clinical administration. When proteins come in contact with vapor–liquid, solid–liquid, and liquid–liquid surfaces, these interfaces can significantly impact the protein drug product quality attrib...

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Detalles Bibliográficos
Autores principales: Li, Jinjiang, Krause, Mary E., Chen, Xiaodong, Cheng, Yuan, Dai, Weiguo, Hill, John J., Huang, Min, Jordan, Susan, LaCasse, Daniel, Narhi, Linda, Shalaev, Evgenyi, Shieh, Ian C., Thomas, Justin C., Tu, Raymond, Zheng, Songyan, Zhu, Lily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
White Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435788/
https://www.ncbi.nlm.nih.gov/pubmed/30915582
http://dx.doi.org/10.1208/s12248-019-0312-3

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