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Mutant p53 regulates LPA signaling through lysophosphatidic acid phosphatase type 6
Emerging evidence has indicated that high-grade serous ovarian cancer (HGSOC) originates in the fallopian tube, where the earliest known genetic lesion is the mutation of TP53. In addition to such genetic changes, HGSOC is characterized by altered metabolism, including the production of oncogenic li...
Autores principales: | Chryplewicz, Agnieszka, Tienda, Samantha M., Nahotko, Dominik A., Peters, Pamela N., Lengyel, Ernst, Eckert, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435808/ https://www.ncbi.nlm.nih.gov/pubmed/30914657 http://dx.doi.org/10.1038/s41598-019-41352-5 |
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