Cargando…

Barrett’s esophagus: novel strategies for screening and surveillance

Barrett’s esophagus is the precursor lesion for esophageal adenocarcinoma. Screening and surveillance of Barrett’s esophagus are undertaken with the goal of earlier detection and lowering the mortality from esophageal adenocarcinoma. The widely used technique is standard esophagogastroduodenoscopy w...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanghi, Vedha, Thota, Prashanthi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435879/
https://www.ncbi.nlm.nih.gov/pubmed/30937155
http://dx.doi.org/10.1177/2040622319837851
_version_ 1783406723013279744
author Sanghi, Vedha
Thota, Prashanthi N.
author_facet Sanghi, Vedha
Thota, Prashanthi N.
author_sort Sanghi, Vedha
collection PubMed
description Barrett’s esophagus is the precursor lesion for esophageal adenocarcinoma. Screening and surveillance of Barrett’s esophagus are undertaken with the goal of earlier detection and lowering the mortality from esophageal adenocarcinoma. The widely used technique is standard esophagogastroduodenoscopy with biopsies per the Seattle protocol for screening and surveillance of Barrett’s esophagus. Surveillance intervals vary depending on the degree of dysplasia with endoscopic eradication therapy confined to patients with Barrett’s esophagus and confirmed dysplasia. In this review, we present various novel techniques for screening of Barrett’s esophagus such as unsedated transnasal endoscopy, cytosponge with trefoil factor-3, balloon cytology, esophageal capsule endoscopy, liquid biopsy, electronic nose, and oral microbiome. In addition, advanced imaging techniques such as narrow band imaging, dye-based chromoendoscopy, confocal laser endomicroscopy, volumetric laser endomicroscopy, and wide-area transepithelial sampling with computer-assisted three-dimensional analysis developed for better detection of dysplasia are also reviewed.
format Online
Article
Text
id pubmed-6435879
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-64358792019-04-01 Barrett’s esophagus: novel strategies for screening and surveillance Sanghi, Vedha Thota, Prashanthi N. Ther Adv Chronic Dis Review Barrett’s esophagus is the precursor lesion for esophageal adenocarcinoma. Screening and surveillance of Barrett’s esophagus are undertaken with the goal of earlier detection and lowering the mortality from esophageal adenocarcinoma. The widely used technique is standard esophagogastroduodenoscopy with biopsies per the Seattle protocol for screening and surveillance of Barrett’s esophagus. Surveillance intervals vary depending on the degree of dysplasia with endoscopic eradication therapy confined to patients with Barrett’s esophagus and confirmed dysplasia. In this review, we present various novel techniques for screening of Barrett’s esophagus such as unsedated transnasal endoscopy, cytosponge with trefoil factor-3, balloon cytology, esophageal capsule endoscopy, liquid biopsy, electronic nose, and oral microbiome. In addition, advanced imaging techniques such as narrow band imaging, dye-based chromoendoscopy, confocal laser endomicroscopy, volumetric laser endomicroscopy, and wide-area transepithelial sampling with computer-assisted three-dimensional analysis developed for better detection of dysplasia are also reviewed. SAGE Publications 2019-03-26 /pmc/articles/PMC6435879/ /pubmed/30937155 http://dx.doi.org/10.1177/2040622319837851 Text en © The Author(s), 2019 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Sanghi, Vedha
Thota, Prashanthi N.
Barrett’s esophagus: novel strategies for screening and surveillance
title Barrett’s esophagus: novel strategies for screening and surveillance
title_full Barrett’s esophagus: novel strategies for screening and surveillance
title_fullStr Barrett’s esophagus: novel strategies for screening and surveillance
title_full_unstemmed Barrett’s esophagus: novel strategies for screening and surveillance
title_short Barrett’s esophagus: novel strategies for screening and surveillance
title_sort barrett’s esophagus: novel strategies for screening and surveillance
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435879/
https://www.ncbi.nlm.nih.gov/pubmed/30937155
http://dx.doi.org/10.1177/2040622319837851
work_keys_str_mv AT sanghivedha barrettsesophagusnovelstrategiesforscreeningandsurveillance
AT thotaprashanthin barrettsesophagusnovelstrategiesforscreeningandsurveillance