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Human-specific dual regulations of FXR-activation for reduction of fatty liver using in vitro cell culture model
Nuclear receptor farnesoid X receptor activation inhibits fatty acid synthesis through the liver X receptor-α-sterol regulatory element binding protein-1c pathway universally in animals, but also has human-specific crosstalk with the peroxisome proliferator-activated receptor-α. The effects of farne...
Autores principales: | Miyazaki, Teruo, Honda, Akira, Ikegami, Tadashi, Iida, Takashi, Matsuzaki, Yasushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
the Society for Free Radical Research Japan
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436045/ https://www.ncbi.nlm.nih.gov/pubmed/30936623 http://dx.doi.org/10.3164/jcbn.18-80 |
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