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Docosahexaenoic Acid Inhibits Inflammation-Induced Osteoclast Formation and Bone Resorption in vivo Through GPR120 by Inhibiting TNF-α Production in Macrophages and Directly Inhibiting Osteoclast Formation
Docosahexaenoic acid (DHA) is an n-3 fatty acid that is an important structural component of the cell membrane. DHA exerts potent anti-inflammatory effects through G protein-coupled receptor 120 (GPR120), which is a functional receptor for n-3 fatty acids. DHA also regulates osteoclast formation and...
Autores principales: | Kishikawa, Akiko, Kitaura, Hideki, Kimura, Keisuke, Ogawa, Saika, Qi, Jiawei, Shen, Wei-Ren, Ohori, Fumitoshi, Noguchi, Takahiro, Marahleh, Aseel, Nara, Yasuhiko, Ichimura, Atsuhiko, Mizoguchi, Itaru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436080/ https://www.ncbi.nlm.nih.gov/pubmed/30949128 http://dx.doi.org/10.3389/fendo.2019.00157 |
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