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CD28 (null) CD4 T-cell expansions in autoimmune disease suggest a link with cytomegalovirus infection
Immunosenescence is thought to contribute to the increase of autoimmune diseases in older people. Immunosenescence is often associated with the presence of an expanded population of CD4 T cells lacking expression of CD28 (CD28 (null)). These highly cytotoxic CD4 T cells were isolated from disease-af...
Autores principales: | Bano, Aalia, Pera, Alejandra, Almoukayed, Ahmad, Clarke, Thomas H.S., Kirmani, Sukaina, Davies, Kevin A., Kern, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436193/ https://www.ncbi.nlm.nih.gov/pubmed/30984377 http://dx.doi.org/10.12688/f1000research.17119.1 |
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