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Chemical Screening Approaches Enabling Drug Discovery of Autophagy Modulators for Biomedical Applications in Human Diseases

Autophagy is an intracellular degradation pathway for malfunctioning aggregation-prone proteins, damaged organelles, unwanted macromolecules and invading pathogens. This process is essential for maintaining cellular and tissue homeostasis that contribute to organismal survival. Autophagy dysfunction...

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Detalles Bibliográficos
Autores principales: Panda, Prashanta Kumar, Fahrner, Alexandra, Vats, Somya, Seranova, Elena, Sharma, Vartika, Chipara, Miruna, Desai, Priyal, Torresi, Jorge, Rosenstock, Tatiana, Kumar, Dhiraj, Sarkar, Sovan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436197/
https://www.ncbi.nlm.nih.gov/pubmed/30949479
http://dx.doi.org/10.3389/fcell.2019.00038