P2RX7 Deletion in T Cells Promotes Autoimmune Arthritis by Unleashing the Tfh Cell Response

Rheumatoid arthritis (RA) is an autoimmune disease that affects ~1% of the world's population. B cells and autoantibodies play an important role in the pathogenesis of RA. The P2RX7 receptor is an ATP-gated cation channel and its activation results in the release of pro-inflammatory molecules....

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Detalles Bibliográficos
Autores principales: Felix, Krysta M., Teng, Fei, Bates, Nicholas A., Ma, Heqing, Jaimez, Ivan A., Sleiman, Kiah C., Tran, Nhan L., Wu, Hsin-Jung Joyce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436202/
https://www.ncbi.nlm.nih.gov/pubmed/30949163
http://dx.doi.org/10.3389/fimmu.2019.00411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436202/
https://www.ncbi.nlm.nih.gov/pubmed/30949163
http://dx.doi.org/10.3389/fimmu.2019.00411

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