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A New Way for Beta Cell Neogenesis: Transdifferentiation from Alpha Cells Induced by Glucagon-Like Peptide 1
Recent studies showed that alpha cells, especially immature cells and proalpha cells, might be the precursors of beta cells. Exposure to glucagon-like peptide 1 (GLP1) can ameliorate hyperglycemia in diabetic mice and restore the beta cell mass. In the present study, we adopted single high-dose (60 ...
Autores principales: | Zhang, Zhen, Hu, Yinghui, Xu, Ningning, Zhou, Wenjun, Yang, Lei, Chen, Rongping, Yang, Rui, Sun, Jia, Chen, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436340/ https://www.ncbi.nlm.nih.gov/pubmed/31001561 http://dx.doi.org/10.1155/2019/2583047 |
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