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Sclerostin Antibody Mitigates Estrogen Deficiency-Inducted Marrow Lipid Accumulation Assessed by Proton MR Spectroscopy

Sclerostin knock-out mice or sclerostin antibody (Scl-Ab) treated wild-type mice displayed decreased marrow adiposity. But the effects of Scl-Ab on estrogen deficiency-induced marrow fat expansion remain elusive. In this work, 45 female New Zealand rabbits were equally divided into sham-operation, o...

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Detalles Bibliográficos
Autores principales: Li, Shaojun, Huang, Bingcang, Jiang, Bo, Gu, Mingjun, Yang, Xiaodan, Yin, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436376/
https://www.ncbi.nlm.nih.gov/pubmed/30949129
http://dx.doi.org/10.3389/fendo.2019.00159