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Compositional epistasis detection using a few prototype disease models
We study computational approaches for detecting SNP-SNP interactions that are characterized by a set of “two-locus, two-allele, two-phenotype and complete-penetrance” disease models. We argue that existing methods, which use data to determine a best-fitting disease model for each pair of SNPs prior...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436689/ https://www.ncbi.nlm.nih.gov/pubmed/30917131 http://dx.doi.org/10.1371/journal.pone.0213236 |