A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation

The epidermal growth factor receptor ligand Amphiregulin has a well-documented role in the restoration of tissue homeostasis after injury; however, the mechanism by which Amphiregulin contributes to wound repair remains unknown. Here we show that Amphiregulin functioned by releasing bioactive transf...

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Detalles Bibliográficos
Autores principales: Minutti, Carlos M., Modak, Rucha V., Macdonald, Felicity, Li, Fengqi, Smyth, Danielle J., Dorward, David A., Blair, Natalie, Husovsky, Connor, Muir, Andrew, Giampazolias, Evangelos, Dobie, Ross, Maizels, Rick M., Kendall, Timothy J., Griggs, David W., Kopf, Manfred, Henderson, Neil C., Zaiss, Dietmar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436929/
https://www.ncbi.nlm.nih.gov/pubmed/30770250
http://dx.doi.org/10.1016/j.immuni.2019.01.008

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