Immunomodulatory nanogels overcome restricted immunity in a murine model of gut microbiome–mediated metabolic syndrome

Biomaterials-based nanovaccines, such as those made of poly(lactic-co-glycolic acid) (PLGA), can induce stronger immunity than soluble antigens in healthy wild-type mouse models. However, whether metabolic syndrome can influence the immunological responses of nanovaccines remains poorly understood....

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Detalles Bibliográficos
Autores principales: Mosquera, Matthew J., Kim, Sungwoong, Zhou, Hao, Jing, Tina T., Luna, Marysol, Guss, Jason D., Reddy, Pooja, Lai, Kristine, Leifer, Cynthia A., Brito, Ilana L., Hernandez, Christopher J., Singh, Ankur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436937/
https://www.ncbi.nlm.nih.gov/pubmed/30944865
http://dx.doi.org/10.1126/sciadv.aav9788

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