Cargando…

A proof-of-concept study for the design of a VLP-based combinatorial HPV and placental malaria vaccine

In Africa, cervical cancer and placental malaria (PM) are a major public health concern. There is currently no available PM vaccine and the marketed Human Papillomavirus (HPV) vaccines are prohibitively expensive. The idea of a combinatorial HPV and PM vaccine is attractive because the target popula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Janitzek, Christoph M., Peabody, Julianne, Thrane, Susan, H. R. Carlsen, Philip, G. Theander, Thor, Salanti, Ali, Chackerian, Bryce, A. Nielsen, Morten, Sander, Adam F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437161/ https://www.ncbi.nlm.nih.gov/pubmed/30918267 http://dx.doi.org/10.1038/s41598-019-41522-5

Ejemplares similares

RNA Phage VLP-Based Vaccine Platforms
por: Peabody, David S., et al.
Publicado: (2021)

Characterization of a spray-dried candidate HPV L2-VLP vaccine stored for multiple years at room temperature
por: Peabody, Julianne, et al.
Publicado: (2017)

A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA
por: Thrane, Susan, et al.
Publicado: (2015)

A Pan-HPV Vaccine Based on Bacteriophage PP7 VLPs Displaying Broadly Cross-Neutralizing Epitopes from the HPV Minor Capsid Protein, L2
por: Tumban, Ebenezer, et al.
Publicado: (2011)

The Immunogenicity of a VLP-based Malaria Vaccine Targeting CSP in Pregnant and Neonatal Mice
por: Jelínková, Lucie, et al.
Publicado: (2023)

A cVLP-Based Vaccine Displaying Full-Length PCSK9 Elicits a Higher Reduction in Plasma PCSK9 Than Similar Peptide-Based cVLP Vaccines
por: Goksøyr, Louise, et al.
Publicado: (2022)

Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses
por: Janitzek, Christoph M., et al.
Publicado: (2016)

The Immunogenicity of Capsid-Like Particle Vaccines in Combination with Different Adjuvants Using Different Routes of Administration
por: Janitzek, Christoph M., et al.
Publicado: (2021)

Identification of an Immunogenic Mimic of a Conserved Epitope on the Plasmodium falciparum Blood Stage Antigen AMA1 Using Virus-Like Particle (VLP) Peptide Display
por: Crossey, Erin, et al.
Publicado: (2015)

VLP-based vaccine induces immune control of Staphylococcus aureus virulence regulation
por: Daly, Seth M., et al.
Publicado: (2017)

Two-component vaccine consisting of virus-like particles displaying hepatitis C virus envelope protein 2 oligomers
por: Prentoe, Jannick, et al.
Publicado: (2022)

VLPs Displaying a Single L2 Epitope Induce Broadly Cross-Neutralizing Antibodies against Human Papillomavirus
por: Tumban, Ebenezer, et al.
Publicado: (2012)

Epitope-Specific Anti-hCG Vaccines on a Virus Like Particle Platform
por: Caldeira, Jerri, et al.
Publicado: (2015)

Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA
por: Resende, Mafalda, et al.
Publicado: (2008)

A Vaccine Displaying a Trimeric Influenza-A HA Stem Protein on Capsid-Like Particles Elicits Potent and Long-Lasting Protection in Mice
por: Thrane, Susan, et al.
Publicado: (2020)

Factors That Govern the Induction of Long-Lived Antibody Responses
por: Chackerian, Bryce, et al.
Publicado: (2020)

Bacterial superglue enables easy development of efficient virus-like particle based vaccines
por: Thrane, Susan, et al.
Publicado: (2016)

Differential Induction of Functional IgG Using the Plasmodium falciparum Placental Malaria Vaccine Candidate VAR2CSA
por: Pinto, Vera V., et al.
Publicado: (2011)

Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria
por: Pehrson, Caroline, et al.
Publicado: (2016)

Freeze-Drying of a Capsid Virus-like Particle-Based Platform Allows Stable Storage of Vaccines at Ambient Temperature
por: Aves, Kara-Lee, et al.
Publicado: (2022)

Virus-like particle display of HER2 induces potent anti-cancer responses
por: Palladini, Arianna, et al.
Publicado: (2018)

Epitope Mapping and Topographic Analysis of VAR2CSA DBL3X Involved in P. falciparum Placental Sequestration
por: Dahlbäck, Madeleine, et al.
Publicado: (2006)

Structural Insight into Epitopes in the Pregnancy-Associated Malaria Protein VAR2CSA
por: Andersen, Pernille, et al.
Publicado: (2008)

Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites
por: Dahlbäck, Madeleine, et al.
Publicado: (2007)

Utilizing Nanobody Technology to Target Non-Immunodominant Domains of VAR2CSA
por: Ditlev, Sisse B., et al.
Publicado: (2014)

Vaccination with VLPs Presenting a Linear Neutralizing Domain of S. aureus Hla Elicits Protective Immunity
por: Joyner, Jason A., et al.
Publicado: (2020)

Immunization with virus-like particles conjugated to CIDRα1 domain of Plasmodium falciparum erythrocyte membrane protein 1 induces inhibitory antibodies
por: Harmsen, Charlotte, et al.
Publicado: (2020)

Engineering an Antibody V Gene-Selective Vaccine
por: Ronsard, Larance, et al.
Publicado: (2021)

RG1-VLP and Other L2-Based, Broad-Spectrum HPV Vaccine Candidates
por: Huber, Bettina, et al.
Publicado: (2021)

Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1
por: Ayres Pereira, Marina, et al.
Publicado: (2016)

Pathogen-specific deep sequence-coupled biopanning: A method for surveying human antibody responses
por: Frietze, Kathryn M., et al.
Publicado: (2017)

Head-to-Head Comparison of Modular Vaccines Developed Using Different Capsid Virus-Like Particle Backbones and Antigen Conjugation Systems
por: Fredsgaard, Laurits, et al.
Publicado: (2021)

Structure function analysis of P. falciparum VAR2CSA
por: Dahlbäck, Madeleine, et al.
Publicado: (2010)

Concepts of combinatorial optimization
por: Paschos, Vangelis Th
Publicado: (2014)

An Upstream Open Reading Frame Controls Translation of var2csa, a Gene Implicated in Placental Malaria
por: Amulic, Borko, et al.
Publicado: (2009)

Parasites modulate the gut-microbiome in insects: A proof-of-concept study
por: Fredensborg, Brian L., et al.
Publicado: (2020)

Chimeric L2-Based Virus-Like Particle (VLP) Vaccines Targeting Cutaneous Human Papillomaviruses (HPV)
por: Huber, Bettina, et al.
Publicado: (2017)

Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding
por: Wang, Kaituo, et al.
Publicado: (2021)

Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA
por: Doritchamou, Justin, et al.
Publicado: (2023)

Use of Mixed Micelles for Presentation of Building Blocks in a New Combinatorial Discovery Methodology: Proof-of-Concept Studies
por: New, Roger, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_c96vakgbum9dkid4f8bosdvnbp