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Determining the extent of maternal-foetal chimerism in cord blood

During pregnancy, maternal T cells can enter the foetus, leading to maternal-foetal chimerism. This phenomenon may affect how leukaemia patients respond to transplantation therapy using stem cells from cord blood (CB). It has been proposed that maternal T cells, primed to inherited paternal HLAs, ar...

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Detalles Bibliográficos
Autores principales: Opstelten, Rianne, Slot, Manon C., Lardy, Neubury M., Lankester, Arjan C., Mulder, Arend, Claas, Frans H. J., van Rood, Jon J., Amsen, Derk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437214/
https://www.ncbi.nlm.nih.gov/pubmed/30918307
http://dx.doi.org/10.1038/s41598-019-41733-w