Diagnosis of fusion genes using targeted RNA sequencing

Fusion genes are a major cause of cancer. Their rapid and accurate diagnosis can inform clinical action, but current molecular diagnostic assays are restricted in resolution and throughput. Here, we show that targeted RNA sequencing (RNAseq) can overcome these limitations. First, we establish that f...

Descripción completa

Detalles Bibliográficos
Autores principales: Heyer, Erin E., Deveson, Ira W., Wooi, Danson, Selinger, Christina I., Lyons, Ruth J., Hayes, Vanessa M., O’Toole, Sandra A., Ballinger, Mandy L., Gill, Devinder, Thomas, David M., Mercer, Tim R., Blackburn, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437215/
https://www.ncbi.nlm.nih.gov/pubmed/30918253
http://dx.doi.org/10.1038/s41467-019-09374-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437215/
https://www.ncbi.nlm.nih.gov/pubmed/30918253
http://dx.doi.org/10.1038/s41467-019-09374-9

Ejemplares similares