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XY oocytes of sex-reversed females with a Sry mutation deviate from the normal developmental process beyond the mitotic stage()
The fertility of sex-reversed XY female mice is severely impaired by a massive loss of oocytes and failure of meiotic progression. This phenomenon remains an outstanding mystery. We sought to determine the molecular etiology of XY oocyte dysfunction by generating sex-reversed females that bear genet...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437265/ https://www.ncbi.nlm.nih.gov/pubmed/30289439 http://dx.doi.org/10.1093/biolre/ioy214 |