Cargando…
Combined Transcriptome and Proteome Analysis of Immortalized Human Keratinocytes Expressing Human Papillomavirus 16 (HPV16) Oncogenes Reveals Novel Key Factors and Networks in HPV-Induced Carcinogenesis
Although the role of high-risk human papillomaviruses (hrHPVs) as etiological agents in cancer development has been intensively studied during the last decades, there is still the necessity of understanding the impact of the HPV E6 and E7 oncogenes on host cells, ultimately leading to malignant tran...
Autores principales: | Yang, Ruwen, Klimentová, Jana, Göckel-Krzikalla, Elke, Ly, Regina, Gmelin, Nadine, Hotz-Wagenblatt, Agnes, Řehulková, Helena, Stulík, Jiří, Rösl, Frank, Niebler, Martina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437273/ https://www.ncbi.nlm.nih.gov/pubmed/30918060 http://dx.doi.org/10.1128/mSphere.00129-19 |
Ejemplares similares
-
Folate Repletion after Deficiency Induces Irreversible Genomic and Transcriptional Changes in Human Papillomavirus Type 16 (HPV16)-Immortalized Human Keratinocytes
por: Savini, Claudia, et al.
Publicado: (2019) -
p53 Is Regulated in a Biphasic Manner in Hypoxic Human Papillomavirus Type 16 (HPV16)-Positive Cervical Cancer Cells
por: Zhuang, Linhan, et al.
Publicado: (2020) -
Partial loss of Smad signaling during in vitro progression of HPV16-immortalized human keratinocytes
por: Altomare, Diego, et al.
Publicado: (2013) -
HPV16 E7 Protein and hTERT Proteins Defective for Telomere Maintenance Cooperate to Immortalize Human Keratinocytes
por: Miller, Jonathan, et al.
Publicado: (2013) -
HPV16-E2 protein modifies self-renewal and differentiation rate in progenitor cells of human immortalized keratinocytes
por: Domínguez-Catzín, Victoria, et al.
Publicado: (2017)