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Effects of elamipretide on skeletal muscle in dogs with experimentally induced heart failure

AIMS: Elamipretide (ELAM), an aromatic–cationic tetrapeptide, interacts with cardiolipin and normalizes dysfunctional mitochondria of cardiomyocytes. This study examined the effects of ELAM on skeletal muscle mitochondria function in dogs with chronic heart failure (HF). METHODS AND RESULTS: Studies...

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Detalles Bibliográficos
Autores principales: Sabbah, Hani N., Gupta, Ramesh C., Singh‐Gupta, Vinita, Zhang, Kefei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437430/
https://www.ncbi.nlm.nih.gov/pubmed/30688415
http://dx.doi.org/10.1002/ehf2.12408