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Tree‐ensemble analysis assesses presence of multifurcations in single cell data

We introduce TreeTop, an algorithm for single cell data analysis to identify and assign a branching score to branch points in biological processes which may have multi‐level branching hierarchies. We demonstrate branch point identification for processes with varying topologies, including T‐cell matu...

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Detalles Bibliográficos
Autores principales: Macnair, Will, De Vargas Roditi, Laura, Ganscha, Stefan, Claassen, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437440/
https://www.ncbi.nlm.nih.gov/pubmed/30918107
http://dx.doi.org/10.15252/msb.20188552

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