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Transcriptional and physiological roles for STAT proteins in leptin action

OBJECTIVES: Leptin acts via its receptor LepRb on specialized neurons in the brain to modulate food intake, energy expenditure, and body weight. LepRb activates signal transducers and activators of transcription (STATs, including STAT1, STAT3, and STAT5) to control gene expression. METHODS: Because...

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Detalles Bibliográficos
Autores principales:	Pan, Warren, Allison, Margaret B., Sabatini, Paul, Rupp, Alan, Adams, Jessica, Patterson, Christa, Jones, Justin C., Olson, David P., Myers, Martin G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437596/ https://www.ncbi.nlm.nih.gov/pubmed/30718218 http://dx.doi.org/10.1016/j.molmet.2019.01.007

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